Dr Basile Chrétien

Senior Pharmacologist
Basile Chrétien

Pharmacoepidemiologist and health-data scientist working at the intersection of drug safety, real-world evidence, biostatistics, AI, and medical education. My research focuses on developing reproducible and privacy-preserving methods to generate evidence on medicines and clinical outcomes from large-scale healthcare data, alongside research in medical education and technology-enhanced learning. I am particularly interested in international and federated health-data research connecting France and Japan. I am a PhD researcher at Nagoya University, with a background spanning pharmacology, toxicology, biostatistics, pharmacovigilance, and medical education. I work across French, Japanese, and English, supporting research, teaching, and collaboration across academic and healthcare systems. I also develop open research infrastructure and scholarly assessment tools, including SigmaCV and Open Editors Plus.

Research summary

  • Open access 0%
  • Mean RCR 1.21.0 = NIH-funded average; biomedical (PMID) works only · mean over 1 works with RCR · small sample — interpret with caution
  • 1 Publications
  • 1 Datasets
  • 2 Software
  • 1 Patents

PositionsPositions

  1. PhD Candidate
    Graduate School of Medicine · Nagoya University
  2. Senior Pharmacologist
    Department of Pharmacology · Centre Hospitalier Universitaire de Caen Normandie

EducationEducation

  1. Master of Public health in Biostatistics
    Medicine · University of Paris-Saclay
  2. Postgraduate Diploma in Pharmacology (equivalent to Board certification)
    Medicine · University of Caen Normandy
  3. Master of Toxicology
    Pharmacy · Université Paris Descartes
  4. PharmD (Hospital Pharmacy)
    Pharmacy · University of Caen Normandy

PublicationsPublications

  1. Desaunay, P., Eslier, M., Alexandre, J., Dreyfus, M., Chrétien, B., & Guenolé, F. (2024). Antidepressants and fetal death: A systematic review and disproportionality analysis in the WHO safety database (VigiBaseⓇ). Psychiatry Research, 339, 116048–116048. https://doi.org/10.1016/j.psychres.2024.116048
    7 citations

DatasetsDatasets

  1. Chretien, B. Open Editors Plus 2026: Editorial Board Composition of 15,000+ Academic Journals. Zenodo (2026) [Dataset]. https://doi.org/10.5281/zenodo.19468382

SoftwareSoftware

  1. Chrétien, B. SigmaCV. Zenodo (2026) [Software]. https://doi.org/10.5281/zenodo.20594123
    Source code · Version v0.4.0 · License: apache-2.0
  2. Dolladille, C., CHRETIEN, B., Normandie, C. H. U. D. C., & Normandie, U. D. C. Vigicaen: A vigibase® Pharmacovigilance Database Toolbox.. Zenodo (2026) [Software]. https://doi.org/10.5281/zenodo.21840167
    Version v2.1.0 · License: cecill-2.1

Pre-registrationsPre-registrations

  1. Chrétien, B. (2026). SigmaCV — disambiguation & CV norms. https://doi.org/10.17605/osf.io/jtgnb
    OAfirst, corresponding0 citations
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    Full text
    Abstract

    This is the preregistration of an observational study examining how researchers are represented in open scholarly data and how they present themselves on academic CVs. It uses SigmaCV, an open-source web application that auto-generates academic CVs from open research data (OpenAlex, ORCID, Crossref, and related sources). Study A (disambiguation error) quantifies how often works automatically attributed to a researcher by open data sources are false positives — not actually theirs — based on participant adjudication, and estimates how correcting these false positives changes the h-index. Study B (metric-display norms) examines whether, when metric display is opt-in with a default of "none," researchers who display any metric choose the h-index more often than field-normalised indicators. The design is a non-interventional secondary analysis of consent-based, pseudonymised platform data from a single worldwide cohort of consenting adult (18+) SigmaCV users; the two studies share one participant pool and one consent. This preregistration fixes only the two confirmatory hypotheses (H1-A, H1-B) and their analyses; all other analyses (predictors of error, name-script and surname-commonness equity, predictive models, latent CV-style classes, biomedical-subgroup descriptives) are exploratory and reported with effect sizes and confidence intervals. Expected outcomes: a participant-adjudicated false-positive attribution rate and its effect on the h-index (with a reference-standard validation substudy and quantitative bias analysis), and the distribution of metric-display choices under an opt-in/default-none regime. Reporting follows STROBE; de-identified, aggregate data and analysis code will be shared consistent with consent. Ethics review is underway at the Nagoya University Graduate School of Medicine Bioethics Review Committee (observational-research panel; pre-review no. CRE-2026-255); data collection begins only after approval.

Grants & FundingGrants & Funding

  1. Machine Learning-Driven Adaptive Problem Based Learning in Psychopharmacology: A Fra nco-Japanese Cross-Cultural Collaboration for Optimizing Medical Education, Nagoya Daigaku (2025–2029)
  2. PARANAC, University of Caen Normandy

PatentsPatents

  1. COMBINATIONS OF ACETAMINOPHEN AND N-ACETYL CYSTEINE FOR THE TREATMENT OF PAIN AND FEVER, CENTRE HOSPITALIER UNIV DE CAEN NORMANDIE [FR] (2023) [EP4238559]

Peer ReviewPeer Review

  1. Naunyn-Schmiedeberg s Archives of Pharmacology — 26 reviews
  2. Scientific Reports — 15 reviews
  3. BMC Pharmacology and Toxicology — 14 reviews
  4. European Journal of Clinical Pharmacology — 4 reviews
  5. DARU Journal of Pharmaceutical Sciences — 4 reviews
  6. Cardiovascular Toxicology — 2 reviews
  7. BMC Oral Health — 2 reviews
  8. BMC Endocrine Disorders — 2 reviews
  9. Clinical Nutrition ESPEN — 2 reviews
  10. Therapeutic Advances in Psychopharmacology — 2 reviews
  11. British Journal of Clinical Pharmacology — 2 reviews
  12. PLoS ONE — 2 reviews
  13. BMC Psychiatry — 3 reviews
  14. BMC Ophthalmology — 1 review
  15. BMC Gastroenterology — 2 reviews
  16. Lung — 1 review
  17. Archives of Dermatological Research — 1 review
  18. Cell Biology and Toxicology — 1 review
  19. Discover Medicine — 1 review
  20. Egyptian Pediatric Association Gazette — 1 review
  21. Clinical Therapeutics — 1 review
  22. Translational Psychiatry — 1 review
  23. Therapeutic Innovation & Regulatory Science — 1 review
  24. Communications Medicine — 1 review
  25. International Journal of Clinical Pharmacy — 1 review
  26. Discover Artificial Intelligence — 1 review
  27. European Child & Adolescent Psychiatry — 1 review
  28. World Journal of Surgical Oncology — 1 review
  29. BMC Neurology — 1 review
  30. BMC Cancer — 1 review
  31. BMC Pediatrics — 1 review
  32. American Journal of Clinical Dermatology — 1 review
  33. BMC Pregnancy and Childbirth — 1 review
  34. Clinical Drug Investigation — 1 review

Service & MembershipsService & Memberships

  1. Affiliated researcher, Neuropresage, Physiopathology and Imaging of Neurological Disorders · neuropresage.fr

Updated Oct 19, 2026 · living CV, updates automatically

Recently added Dolladille, C., CHRETIEN, B., Normandie, C. H. U. D. C., & Normandie, U. D. C. Vigicaen: A vigibase® Pharmacovigilance Database Toolbox.. Zenodo (2026) [Software]. https://doi.org/10.5281/zenodo.21840

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